By Gribble Gordon W. and Joule John A. (Eds.)
This is often the 16th annual quantity of growth in Heterocyclic Chemistry, and covers the literature released in the course of 2003 on lots of the very important heterocyclic ring systems.This quantity opens with really good reports. the 1st covers 'Lamellarins: Isolation, task and synthesis' an important team of biologically energetic marine alkaloids and the second one discusses 'Radical Additions to Pyridines, Quinolines and Isoquinolines'. the remainder chapters learn the hot literature at the universal heterocycles so as of accelerating ring measurement and the heteroatoms current.
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Additional resources for A critical review of the 2003 literature preceded by two chapters on current heterocyclic topics
Arnoldi, A. Citterio, F. Minisci, J. Chem. , Perkin Trans. 2 1983, 531. G. Castaldi, F. Minisci, V. Tortelli, E. Vismara, Tetrahedron Lett. 1984, 25, 3897. V. Scriven, Comp. Heterocycl. , I sl edn. 1984, 2, 293. A. Russell, D. K. Khanna, J. Org. Chem. 1985, 50, 3423. A. Citterio, A. Gentile, F. Minisci, M. Serravalle, S. Ventura, Tetrahedron 1985, 41,617. K. P. Sloan, V. Snieckus, Tetrahedron Lett. 1985, 26, 6001. C. Giordano, F. Minisci, E. Vismara, S. Levi, J. Org. Chem. 1986, 51,536. F. Minisci, E.
Minisci, K. Ogawa, Tetrahedron 1976, 32, 2741. F. Minisci, Top. Curr. Chem. 1976, 62, 1. F. Minisci, A. Citterio, Adv. Free Rad. Chem. 1980, 6, 65. F. Minisci, A. Citterio, C. Giordano, Acc. Chem. Res. 1983, 16, 27. C. Arnoldi, A. Citterio, F. Minisci, J. Chem. , Perkin Trans. 2 1983, 531. G. Castaldi, F. Minisci, V. Tortelli, E. Vismara, Tetrahedron Lett. 1984, 25, 3897. V. Scriven, Comp. Heterocycl. , I sl edn. 1984, 2, 293. A. Russell, D. K. Khanna, J. Org. Chem. 1985, 50, 3423. A. Citterio, A.
Indeed, aminopyridine 144 was formed as the major product in 60% yield. However, through the simple expedient of adding potassium carbonate to the solution of aminide 142, that reduction pathway was almost completely shut down and the yield of pyrazolopyridine 143 was elevated from 2% to 56% (Scheme 39). CI 2 equiv. (Me3Si)SiH 142 2 equiv. AIBN MeCN, Phil K2CO3, 80 ~ 24 h CI H2N 143, 56% 144, 5 % Scheme 39 The reaction has also been used to synthesise pyridopyrazolepyrazine 146 (Scheme 40). Here too, adding potassium carbonate to the solution of aminide 145 proved to be crucial for achieving a successful cyclisation reaction.
A critical review of the 2003 literature preceded by two chapters on current heterocyclic topics by Gribble Gordon W. and Joule John A. (Eds.)